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Symbol Name ID |
Ccr7
C-C motif chemokine receptor 7 MGI:103011 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
abnormal dendritic cell chemotaxis |
abnormal leukocyte migration |
parotid gland inflammation |
submandibular gland inflammation |
salivary gland inflammation |
abnormal thymus cortex morphology |
small thymus medulla |
lacrimal gland inflammation |
enlarged spleen |
abnormal class switch recombination |
decreased CD103-positive CD11b-low dendritic cell number |
decreased CD11b-high dendritic cell number |
decreased dendritic cell number |
decreased CD4-positive, alpha-beta T cell number |
increased CD4-positive, alpha-beta T cell number |
decreased T cell number |
increased T cell number |
increased single-positive T cell number |
decreased macrophage cell number |
abnormal spleen red pulp morphology |
abnormal spleen marginal sinus morphology |
abnormal spleen periarteriolar lymphoid sheath morphology |
abnormal B cell physiology |
abnormal B cell activation |
increased IgE level |
increased IgG1 level |
increased IgG2a level |
decreased IgG3 level |
abnormal T cell physiology |
abnormal Peyer's patch T cell area morphology |
small Peyer's patches |
abnormal lymph node cortex morphology |
abnormal lymph node germinal center morphology |
abnormal lymph node T cell domain morphology |
small lymph nodes |
abnormal dendritic cell physiology |
decreased susceptibility to type IV hypersensitivity reaction |
abnormal humoral immune response |
increased susceptibility to autoimmune disorder |
chronic inflammation |
increased inflammatory response |
decreased susceptibility to bacterial infection |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||
| Ccr7m1Btlr/Ccr7m1Btlr | ||||||||||||||||||||||||||||||||||||||||||||
| Ccr7tm1Dgen/Ccr7tm1Dgen | ||||||||||||||||||||||||||||||||||||||||||||
| Ccr7tm1Rfor/Ccr7tm1Rfor | * | |||||||||||||||||||||||||||||||||||||||||||
| Ccr7m1Btlr/Ccr7+ | ||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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